The first such method was developed in biophysicist Steve Quake’s lab at Caltech and commercialized by Helicos Biosciences, but became unavailable after the company declared bankruptcy, saddled by legal issues and unable to find a market niche. These days, the canonical technique comes from a company called Pacific Biosciences (PacBio). Scientists often refer to single-molecule techniques as “third-generation” DNA sequencing, though they’re often also lumped into the NGS bucket with Illumina.
AI-supported smart mappingThe introduction of LiDAR smart mapping in the 2010s transformed the way that robot vacuums get around our homes. Instead of playing bumper cars with furniture and hoping for the best, LiDAR robot vacuums bounce laser pulses off of walls and large objects to create a precise 3D map of your home. This was the breakthrough that brought us room-by-room cleaning, zone cleaning, and no-go zones without those ugly physical barrier strips.
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