90% of AI projects fail - here are 3 ways to ensure yours doesn't
运动能护脑，是谁在发挥作用？首先，作者对 6 月龄 APP/PS1 小鼠进行 4 周游泳运动，经免疫组织化学染色、水迷宫实验等发现，小鼠脑内淀粉样斑块减少、认知功能提升。通过流式细胞术、蛋白质印迹等检测，运动后小胶质细胞中 DAM 标志物（Trem2、CD11c 等）的蛋白和 mRNA 表达均升高。而用PLX5622耗竭小胶质细胞后，运动的保护作用消失，小鼠认知能力下降、淀粉样斑块积累，说明小胶质细胞是运动改善 AD 认知的关键。
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3. 做溯因更新：让假说更好解释当前证据状态，更多细节参见谷歌
Today’s legal action comes after several weeks of back-and-forth between the AI company and the government. In late February, news broke that the Department of Defense and Defense Secretary Pete Hegseth were pressuring Anthropic to remove certain safeguards from its AI systems, but Amodei made it clear the company would refuse to allow its model to be used for mass surveillance or development of autonomous weapons.